In 2021, there were 125,147 deaths in Portugal, more 1,468 (1.2%) deaths compared with 2020 and more 12,856 (11.4%) deaths compared with 2019. The number of deaths from COVID-19 registered in 2021 was 12,004 (6,972 in 2020), accounting for 9.6% of all deaths.

In January 2022, the number of deaths was 11,690, higher than that registered in December 2021 (245 more deaths) and lower in 7,981 deaths (-40,6%) than in January 2021. The number of deaths due to COVID-19 increased to 972, accounting for 8.3% of all deaths. The number of deaths due to COVID-19 increased compared with December 2021 (454 more deaths) and decreased compared with January 2021 (4,813 fewer deaths).

In December 2021, 6,875 children were born alive, corresponding to an increase of 9.4%, when compared to the same month of 2020. The total number of live births registered in 2021 was 79,692, lower than those recorded in the same period of 2019 and 2020, respectively, 7,334 and 4,999 less live births.

In December 2021, the natural balance was -4,542, less negative when compared with the same month of 2020, when it recorded the value of -6,703. The natural balance in 2021 was  -45,289, worse regarding the same period of 2019 (-25,214) and 2020 (-38,932).

In December 2021, 2,107 marriages were celebrated, which represents an increase of 40.6% (608 more marriages) when compared with December 2020. In 2021, 29,045 marriages were celebrated, 10,143 more than in same period of 2020 and 4,227 less than in the same period of 2019.